Structural neuroimaging differentiates vulnerability from disease manifestation in colombian families with Huntington's disease

Applying Bioinfomatics Strategies in Huntingtons Disease Research

Nekam’s Disease with Clinical Manifestation Simulating Darier's Disease: A Case Report

Nekam's disease is a rare dermatosis characterized by a distinctive seborrheic dermatitis with prominent facial eruption.  It is further associated with violaceous, papular, and/or nodular lesions on the extremities and trunk, typically arranged in a linear and reticulate pattern.  Herein, describe a patient with Nekam's disease, which resembled Darier’s disease in clinical manifestation.  The ...

molecular analysis of the (cag)n repeat causing huntingtons disease in 66 iranian families

huntington’s disease (hd) is an inherited neurodegenerative disorder characterized by chorea and progressive dementia. the mutation causing the disease has been identified as an unstable expansion of a tri-nucleotide (cag) n at the 5 end of the it 15 gene on chromosome 4. we analyzed the distribution of cag repeats in 66 iranian patients belonging to 66 unrelated families. we found one expanded...

Structural neuroimaging in Alzheimer's disease: do white matter hyperintensities matter?

The targeted brain dysfunction that accompanies aging can have a devastating effect on cognitive and intellectual abilities. A significant proportion of older adults experience precipitous cognitive decline that negatively impacts functional activities. Such individuals meet clinical diagnostic criteria for dementia, which is commonly attributed to Alzheimer's disease (AD). Structural neuroimag...

Causes of pediatric heart disease in Rasht and its relationship with clinical ‎manifestation and demographic characteristic

Introduction: Heart disease is the fifth cause of death in infants and children and ‎‏%90‏‎ of ‎these causes are related to congenital heart diseases.Nearly‏%20‏‎ of these children experience ‎heart failure and surgery, but life expectancy for these children is increased by palliative and ‎corrective surgeries. Demographic characteristics and clinical sym...